| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 290 | 36 | 29 | 0.262 | 0.307 | -0.10 | 2B |
| Manny Ramirez | 264 | 43 | 47 | 0.302 | 0.386 | 3.15 | LF |
| Kevin Youkilis | 260 | 39 | 38 | 0.299 | 0.365 | 1.88 | 1B-3B |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.53 | DH |
| Jacoby Ellsbury | 226 | 40 | 22 | 0.284 | 0.376 | 1.11 | CF-LF-RF |
| Julio Lugo | 213 | 18 | 13 | 0.269 | 0.357 | -1.83 | SS |
| J.D. Drew | 210 | 41 | 32 | 0.318 | 0.419 | 2.65 | RF |
| Jason Varitek | 194 | 15 | 21 | 0.257 | 0.330 | -0.85 | CR |
| Mike Lowell | 193 | 24 | 29 | 0.271 | 0.316 | 0.96 | 3B |
| Coco Crisp | 161 | 16 | 14 | 0.260 | 0.298 | -0.69 | CF |
| Sean Casey | 94 | 6 | 8 | 0.372 | 0.426 | -0.77 | 1B-DH |
| Kevin Cash | 68 | 4 | 6 | 0.279 | 0.338 | -0.57 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Alex Cora | 42 | 3 | 2 | 0.324 | 0.405 | -0.48 | SS |
| Brandon Moss | 34 | 4 | 3 | 0.267 | 0.353 | -0.08 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 82.3 | 3.50 | 14 | 0 | X | 1.39 |
| Tim Wakefield | 81.0 | 4.33 | 13 | 0 | X | -0.21 |
| Josh Beckett | 73.0 | 4.07 | 11 | 0 | X | 0.26 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.29 |
| Jonathan Papelbon | 29.0 | 1.86 | 0 | 28 | X | 1.60 |
| David Aardsma | 28.3 | 3.18 | 0 | 25 | X | 0.69 |
| Hideki Okajima | 27.7 | 1.95 | 0 | 26 | X | 1.47 |
| Manny Delcarmen | 25.0 | 4.32 | 0 | 28 | X | -0.06 |
| Justin Masterson | 24.3 | 2.59 | 4 | 0 | X | 0.93 |
| Javier Lopez | 23.3 | 2.70 | 0 | 30 | X | 0.83 |
| Bartolo Colon | 23.0 | 3.91 | 4 | 0 | X | 0.17 |
| Mike Timlin | 18.3 | 5.89 | 0 | 20 | X | -0.71 |
| Craig Hansen | 16.7 | 4.32 | 0 | 15 | X | -0.04 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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