| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 286 | 36 | 29 | 0.265 | 0.308 | 0.02 | 2B |
| Manny Ramirez | 255 | 40 | 45 | 0.301 | 0.380 | 2.86 | LF |
| Kevin Youkilis | 252 | 39 | 36 | 0.300 | 0.369 | 1.88 | 1B-3B |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.55 | DH |
| Jacoby Ellsbury | 226 | 40 | 22 | 0.284 | 0.376 | 1.14 | CF-LF-RF |
| Julio Lugo | 204 | 17 | 13 | 0.267 | 0.353 | -1.70 | SS |
| J.D. Drew | 201 | 37 | 28 | 0.310 | 0.413 | 2.05 | RF |
| Jason Varitek | 191 | 15 | 21 | 0.262 | 0.335 | -0.76 | CR |
| Mike Lowell | 189 | 23 | 27 | 0.272 | 0.317 | 0.76 | 3B |
| Coco Crisp | 153 | 15 | 13 | 0.254 | 0.294 | -0.70 | CF |
| Sean Casey | 90 | 6 | 8 | 0.378 | 0.433 | -0.67 | 1B-DH |
| Kevin Cash | 63 | 4 | 6 | 0.298 | 0.349 | -0.45 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Alex Cora | 38 | 1 | 1 | 0.303 | 0.395 | -0.69 | SS |
| Brandon Moss | 26 | 3 | 3 | 0.280 | 0.308 | 0.01 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 82.3 | 3.50 | 14 | 0 | X | 1.37 |
| Tim Wakefield | 74.0 | 4.50 | 12 | 0 | X | -0.50 |
| Josh Beckett | 73.0 | 4.07 | 11 | 0 | X | 0.24 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.51 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.30 |
| David Aardsma | 28.3 | 3.18 | 0 | 25 | X | 0.68 |
| Jonathan Papelbon | 27.0 | 2.00 | 0 | 26 | X | 1.39 |
| Hideki Okajima | 26.7 | 2.02 | 0 | 25 | X | 1.36 |
| Manny Delcarmen | 25.0 | 4.32 | 0 | 28 | X | -0.06 |
| Javier Lopez | 23.3 | 2.70 | 0 | 30 | X | 0.82 |
| Bartolo Colon | 23.0 | 3.91 | 4 | 0 | X | 0.16 |
| Justin Masterson | 18.3 | 2.95 | 3 | 0 | X | 0.54 |
| Mike Timlin | 18.3 | 5.89 | 0 | 20 | X | -0.72 |
| Craig Hansen | 14.7 | 4.91 | 0 | 13 | X | -0.24 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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