| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 282 | 36 | 29 | 0.270 | 0.312 | 0.12 | 2B |
| Manny Ramirez | 255 | 40 | 45 | 0.301 | 0.380 | 2.86 | LF |
| Kevin Youkilis | 248 | 39 | 36 | 0.306 | 0.375 | 1.97 | 1B-3B |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.55 | DH |
| Jacoby Ellsbury | 226 | 40 | 22 | 0.284 | 0.376 | 1.13 | CF-LF-RF |
| Julio Lugo | 200 | 17 | 13 | 0.272 | 0.355 | -1.61 | SS |
| J.D. Drew | 197 | 37 | 28 | 0.303 | 0.406 | 2.14 | RF |
| Jason Varitek | 187 | 15 | 21 | 0.262 | 0.337 | -0.67 | CR |
| Mike Lowell | 185 | 23 | 27 | 0.276 | 0.319 | 0.85 | 3B |
| Coco Crisp | 149 | 15 | 13 | 0.261 | 0.302 | -0.60 | CF |
| Sean Casey | 86 | 6 | 8 | 0.359 | 0.419 | -0.58 | 1B-DH |
| Kevin Cash | 63 | 4 | 6 | 0.298 | 0.349 | -0.45 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Alex Cora | 38 | 1 | 1 | 0.303 | 0.395 | -0.69 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.11 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 82.3 | 3.50 | 14 | 0 | X | 1.40 |
| Tim Wakefield | 74.0 | 4.50 | 12 | 0 | X | -0.47 |
| Josh Beckett | 73.0 | 4.07 | 11 | 0 | X | 0.27 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.29 |
| David Aardsma | 27.3 | 2.63 | 0 | 24 | X | 1.02 |
| Jonathan Papelbon | 27.0 | 2.00 | 0 | 26 | X | 1.40 |
| Hideki Okajima | 26.7 | 2.02 | 0 | 25 | X | 1.37 |
| Manny Delcarmen | 25.0 | 4.32 | 0 | 28 | X | -0.06 |
| Javier Lopez | 20.3 | 3.10 | 0 | 29 | X | 0.53 |
| Justin Masterson | 18.3 | 2.95 | 3 | 0 | X | 0.55 |
| Mike Timlin | 18.3 | 5.89 | 0 | 20 | X | -0.71 |
| Bartolo Colon | 18.0 | 3.50 | 3 | 0 | X | 0.30 |
| Craig Hansen | 14.7 | 4.91 | 0 | 13 | X | -0.23 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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