| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 273 | 34 | 28 | 0.275 | 0.311 | 0.02 | 2B |
| Manny Ramirez | 247 | 39 | 39 | 0.295 | 0.372 | 2.32 | LF |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.55 | DH |
| Kevin Youkilis | 241 | 38 | 35 | 0.305 | 0.373 | 1.93 | 1B-3B |
| Jacoby Ellsbury | 219 | 39 | 21 | 0.284 | 0.379 | 1.09 | CF-LF-RF |
| Julio Lugo | 192 | 16 | 13 | 0.275 | 0.354 | -1.52 | SS |
| J.D. Drew | 188 | 34 | 26 | 0.296 | 0.394 | 1.83 | RF |
| Jason Varitek | 179 | 15 | 21 | 0.269 | 0.346 | -0.48 | CR |
| Mike Lowell | 177 | 23 | 27 | 0.284 | 0.328 | 1.04 | 3B |
| Coco Crisp | 144 | 13 | 12 | 0.250 | 0.285 | -0.80 | CF |
| Sean Casey | 82 | 6 | 8 | 0.351 | 0.415 | -0.48 | 1B-DH |
| Kevin Cash | 62 | 4 | 6 | 0.304 | 0.355 | -0.42 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Alex Cora | 38 | 1 | 1 | 0.303 | 0.395 | -0.69 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.11 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 76.0 | 3.67 | 13 | 0 | X | 0.99 |
| Tim Wakefield | 74.0 | 4.50 | 12 | 0 | X | -0.47 |
| Josh Beckett | 67.0 | 4.30 | 10 | 0 | X | -0.11 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.28 |
| Jonathan Papelbon | 27.0 | 2.00 | 0 | 26 | X | 1.40 |
| David Aardsma | 26.3 | 2.73 | 0 | 23 | X | 0.92 |
| Hideki Okajima | 25.7 | 2.10 | 0 | 24 | X | 1.27 |
| Manny Delcarmen | 24.0 | 4.50 | 0 | 27 | X | -0.15 |
| Javier Lopez | 20.3 | 3.10 | 0 | 29 | X | 0.54 |
| Justin Masterson | 18.3 | 2.95 | 3 | 0 | X | 0.55 |
| Bartolo Colon | 18.0 | 3.50 | 3 | 0 | X | 0.31 |
| Mike Timlin | 16.7 | 6.48 | 0 | 19 | X | -0.88 |
| Craig Hansen | 13.7 | 5.27 | 0 | 12 | X | -0.33 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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