| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 269 | 34 | 28 | 0.278 | 0.312 | 0.13 | 2B |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.57 | DH |
| Manny Ramirez | 243 | 37 | 39 | 0.296 | 0.374 | 2.22 | LF |
| Kevin Youkilis | 237 | 37 | 35 | 0.305 | 0.371 | 1.94 | 1B-3B |
| Jacoby Ellsbury | 215 | 39 | 20 | 0.287 | 0.381 | 1.10 | CF-LF-RF |
| Julio Lugo | 189 | 16 | 13 | 0.279 | 0.354 | -1.44 | SS |
| J.D. Drew | 184 | 32 | 25 | 0.288 | 0.386 | 1.62 | RF |
| Jason Varitek | 175 | 14 | 20 | 0.269 | 0.349 | -0.58 | CR |
| Mike Lowell | 173 | 22 | 25 | 0.285 | 0.329 | 0.83 | 3B |
| Coco Crisp | 140 | 13 | 10 | 0.250 | 0.286 | -0.90 | CF |
| Sean Casey | 82 | 6 | 8 | 0.351 | 0.415 | -0.47 | 1B-DH |
| Kevin Cash | 62 | 4 | 6 | 0.304 | 0.355 | -0.42 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.23 | SS-3B |
| Alex Cora | 38 | 1 | 1 | 0.303 | 0.395 | -0.69 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.11 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 76.0 | 3.67 | 13 | 0 | X | 0.98 |
| Tim Wakefield | 74.0 | 4.50 | 12 | 0 | X | -0.47 |
| Josh Beckett | 67.0 | 4.30 | 10 | 0 | X | -0.11 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.29 |
| David Aardsma | 26.3 | 2.73 | 0 | 23 | X | 0.92 |
| Jonathan Papelbon | 26.0 | 2.08 | 0 | 25 | X | 1.30 |
| Hideki Okajima | 25.7 | 2.10 | 0 | 24 | X | 1.27 |
| Manny Delcarmen | 23.0 | 4.70 | 0 | 26 | X | -0.25 |
| Javier Lopez | 20.3 | 3.10 | 0 | 28 | X | 0.54 |
| Bartolo Colon | 18.0 | 3.50 | 3 | 0 | X | 0.31 |
| Mike Timlin | 16.7 | 6.48 | 0 | 19 | X | -0.88 |
| Craig Hansen | 12.7 | 5.68 | 0 | 11 | X | -0.43 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Justin Masterson | 12.3 | 1.46 | 2 | 0 | X | 0.80 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
_