| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 245 | 31 | 27 | 0.288 | 0.322 | 0.24 | 2B |
| David Ortiz | 228 | 34 | 40 | 0.247 | 0.355 | 2.33 | DH |
| Kevin Youkilis | 217 | 32 | 35 | 0.306 | 0.369 | 1.85 | 1B-3B |
| Manny Ramirez | 214 | 31 | 31 | 0.291 | 0.374 | 1.40 | LF |
| Jacoby Ellsbury | 189 | 37 | 19 | 0.278 | 0.376 | 1.37 | CF-LF-RF |
| J.D. Drew | 170 | 31 | 22 | 0.290 | 0.388 | 1.51 | RF |
| Julio Lugo | 169 | 16 | 13 | 0.289 | 0.355 | -0.99 | SS |
| Jason Varitek | 156 | 14 | 19 | 0.275 | 0.359 | -0.26 | CR |
| Mike Lowell | 145 | 18 | 20 | 0.276 | 0.324 | 0.53 | 3B |
| Coco Crisp | 116 | 13 | 10 | 0.287 | 0.310 | -0.35 | CF |
| Sean Casey | 73 | 6 | 8 | 0.348 | 0.411 | -0.27 | 1B-DH |
| Kevin Cash | 57 | 4 | 5 | 0.314 | 0.368 | -0.42 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Alex Cora | 29 | 0 | 1 | 0.385 | 0.448 | -0.59 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.10 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 71.0 | 3.55 | 12 | 0 | X | 1.14 |
| Josh Beckett | 61.0 | 4.43 | 9 | 0 | X | -0.27 |
| Daisuke Matsuzaka | 60.0 | 2.40 | 10 | 0 | X | 2.58 |
| Tim Wakefield | 59.0 | 5.19 | 10 | 0 | X | -1.30 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.27 |
| Jonathan Papelbon | 24.0 | 2.25 | 0 | 23 | X | 1.11 |
| David Aardsma | 23.0 | 3.13 | 0 | 21 | X | 0.60 |
| Hideki Okajima | 21.0 | 0.86 | 0 | 20 | X | 1.66 |
| Manny Delcarmen | 19.3 | 5.59 | 0 | 23 | X | -0.61 |
| Javier Lopez | 18.7 | 3.37 | 0 | 25 | X | 0.38 |
| Mike Timlin | 15.0 | 6.60 | 0 | 17 | X | -0.83 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Justin Masterson | 12.3 | 1.46 | 2 | 0 | X | 0.80 |
| Bartolo Colon | 12.0 | 2.25 | 2 | 0 | X | 0.56 |
| Craig Hansen | 10.0 | 7.20 | 0 | 9 | X | -0.69 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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