| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 228 | 28 | 25 | 0.300 | 0.333 | 0.19 | 2B |
| David Ortiz | 212 | 31 | 38 | 0.247 | 0.349 | 2.24 | DH |
| Kevin Youkilis | 206 | 32 | 35 | 0.324 | 0.388 | 2.17 | 1B-3B |
| Manny Ramirez | 202 | 30 | 28 | 0.287 | 0.371 | 1.32 | LF |
| Jacoby Ellsbury | 171 | 37 | 17 | 0.291 | 0.392 | 1.64 | CF-LF-RF |
| Julio Lugo | 158 | 13 | 13 | 0.293 | 0.354 | -1.00 | SS |
| J.D. Drew | 155 | 30 | 22 | 0.290 | 0.394 | 1.80 | RF |
| Jason Varitek | 145 | 14 | 18 | 0.295 | 0.372 | -0.06 | CR |
| Mike Lowell | 130 | 18 | 19 | 0.283 | 0.331 | 0.82 | 3B |
| Coco Crisp | 113 | 13 | 10 | 0.295 | 0.319 | -0.25 | CF |
| Sean Casey | 69 | 6 | 8 | 0.355 | 0.420 | -0.16 | 1B-DH |
| Kevin Cash | 54 | 4 | 5 | 0.333 | 0.389 | -0.33 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.23 | SS-3B |
| Alex Cora | 25 | 0 | 1 | 0.409 | 0.480 | -0.48 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.11 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 66.0 | 3.41 | 11 | 0 | X | 1.22 |
| Daisuke Matsuzaka | 60.0 | 2.40 | 10 | 0 | X | 2.52 |
| Tim Wakefield | 54.0 | 4.33 | 9 | 0 | X | -0.16 |
| Josh Beckett | 54.0 | 4.67 | 8 | 0 | X | -0.58 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.31 |
| Jonathan Papelbon | 23.0 | 2.35 | 0 | 22 | X | 1.00 |
| David Aardsma | 22.0 | 3.27 | 0 | 20 | X | 0.48 |
| Hideki Okajima | 20.0 | 0.90 | 0 | 19 | X | 1.54 |
| Manny Delcarmen | 18.3 | 5.40 | 0 | 22 | X | -0.51 |
| Javier Lopez | 18.3 | 2.95 | 0 | 24 | X | 0.54 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Justin Masterson | 12.3 | 1.46 | 2 | 0 | X | 0.79 |
| Mike Timlin | 12.0 | 8.25 | 0 | 15 | X | -1.13 |
| Craig Hansen | 8.3 | 7.56 | 0 | 8 | X | -0.65 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| Bartolo Colon | 5.0 | 3.60 | 1 | 0 | X | 0.07 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.63 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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