| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 128 | 14 | 13 | 0.310 | 0.352 | -0.23 | 2B |
| Kevin Youkilis | 115 | 16 | 15 | 0.316 | 0.400 | 0.51 | 1B-3B |
| David Ortiz | 115 | 17 | 20 | 0.172 | 0.287 | 1.14 | DH |
| Manny Ramirez | 113 | 18 | 20 | 0.343 | 0.407 | 1.29 | LF |
| Julio Lugo | 100 | 7 | 7 | 0.287 | 0.320 | -0.92 | SS |
| J.D. Drew | 93 | 18 | 13 | 0.269 | 0.376 | 1.03 | RF |
| Jacoby Ellsbury | 92 | 18 | 11 | 0.280 | 0.391 | 0.85 | CF-LF-RF |
| Jason Varitek | 75 | 6 | 6 | 0.243 | 0.293 | -0.53 | CR |
| Coco Crisp | 59 | 6 | 5 | 0.291 | 0.305 | -0.26 | CF |
| Sean Casey | 59 | 6 | 8 | 0.346 | 0.424 | 0.06 | 1B-DH |
| Mike Lowell | 37 | 1 | 0 | 0.182 | 0.270 | -0.78 | 3B |
| Jed Lowrie | 36 | 4 | 5 | 0.323 | 0.361 | 0.08 | SS-3B |
| Kevin Cash | 35 | 2 | 3 | 0.323 | 0.371 | -0.31 | CR |
| Brandon Moss | 10 | 1 | 2 | 0.300 | 0.300 | 0.08 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Alex Cora | 5 | 0 | 0 | 1.000 | 1.000 | -0.12 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 39.7 | 4.31 | 7 | 0 | X | -0.09 |
| Tim Wakefield | 31.0 | 4.06 | 5 | 0 | X | 0.11 |
| Daisuke Matsuzaka | 28.7 | 3.14 | 5 | 0 | X | 0.72 |
| Clay Buchholz | 28.7 | 4.08 | 5 | 0 | X | 0.09 |
| Josh Beckett | 26.3 | 4.10 | 4 | 0 | X | 0.07 |
| David Aardsma | 13.7 | 3.29 | 0 | 12 | X | 0.29 |
| Jonathan Papelbon | 12.0 | 2.25 | 0 | 11 | X | 0.55 |
| Manny Delcarmen | 11.7 | 5.40 | 0 | 13 | X | -0.32 |
| Julian Tavarez | 10.3 | 5.23 | 0 | 7 | X | -0.24 |
| Javier Lopez | 10.0 | 4.50 | 0 | 13 | X | -0.07 |
| Hideki Okajima | 9.3 | 0.96 | 0 | 10 | X | 0.71 |
| Mike Timlin | 6.0 | 13.50 | 0 | 9 | X | -1.30 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| Justin Masterson | 6.0 | 1.50 | 1 | 0 | X | 0.38 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
| Craig Hansen | 1.7 | 5.40 | 0 | 1 | X | -0.05 |
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