| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 120 | 14 | 13 | 0.324 | 0.367 | -0.03 | 2B |
| David Ortiz | 111 | 16 | 20 | 0.177 | 0.288 | 1.13 | DH |
| Kevin Youkilis | 108 | 16 | 14 | 0.319 | 0.407 | 0.57 | 1B-3B |
| Manny Ramirez | 106 | 18 | 20 | 0.354 | 0.415 | 1.46 | LF |
| Julio Lugo | 94 | 7 | 7 | 0.295 | 0.330 | -0.78 | SS |
| J.D. Drew | 89 | 18 | 13 | 0.284 | 0.393 | 1.13 | RF |
| Jacoby Ellsbury | 88 | 18 | 11 | 0.296 | 0.409 | 0.94 | CF-LF-RF |
| Jason Varitek | 69 | 6 | 6 | 0.250 | 0.304 | -0.39 | CR |
| Sean Casey | 59 | 6 | 8 | 0.346 | 0.424 | 0.06 | 1B-DH |
| Coco Crisp | 52 | 6 | 5 | 0.333 | 0.346 | -0.09 | CF |
| Kevin Cash | 35 | 2 | 3 | 0.323 | 0.371 | -0.31 | CR |
| Mike Lowell | 34 | 1 | 0 | 0.200 | 0.294 | -0.71 | 3B |
| Jed Lowrie | 33 | 4 | 5 | 0.357 | 0.394 | 0.16 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Brandon Moss | 8 | 1 | 2 | 0.250 | 0.250 | 0.12 | LF-RF |
| Alex Cora | 5 | 0 | 0 | 1.000 | 1.000 | -0.12 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 31.7 | 5.40 | 6 | 0 | X | -0.84 |
| Tim Wakefield | 31.0 | 4.06 | 5 | 0 | X | 0.14 |
| Clay Buchholz | 28.7 | 4.08 | 5 | 0 | X | 0.12 |
| Daisuke Matsuzaka | 28.7 | 3.14 | 5 | 0 | X | 0.75 |
| Josh Beckett | 19.3 | 5.12 | 3 | 0 | X | -0.39 |
| David Aardsma | 13.7 | 3.29 | 0 | 12 | X | 0.31 |
| Jonathan Papelbon | 11.0 | 2.45 | 0 | 10 | X | 0.46 |
| Manny Delcarmen | 10.7 | 5.06 | 0 | 12 | X | -0.20 |
| Julian Tavarez | 10.3 | 5.23 | 0 | 7 | X | -0.23 |
| Javier Lopez | 10.0 | 4.50 | 0 | 13 | X | -0.06 |
| Hideki Okajima | 9.3 | 0.96 | 0 | 10 | X | 0.72 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| Justin Masterson | 6.0 | 1.50 | 1 | 0 | X | 0.39 |
| Mike Timlin | 6.0 | 13.50 | 0 | 9 | X | -1.29 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
| Craig Hansen | 1.7 | 5.40 | 0 | 1 | X | -0.04 |
_