| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 116 | 14 | 13 | 0.337 | 0.379 | 0.08 | 2B |
| David Ortiz | 111 | 16 | 20 | 0.177 | 0.288 | 1.15 | DH |
| Kevin Youkilis | 104 | 16 | 14 | 0.330 | 0.413 | 0.68 | 1B-3B |
| Manny Ramirez | 102 | 18 | 20 | 0.370 | 0.431 | 1.57 | LF |
| Julio Lugo | 91 | 7 | 7 | 0.306 | 0.341 | -0.69 | SS |
| J.D. Drew | 85 | 18 | 13 | 0.282 | 0.388 | 1.24 | RF |
| Jacoby Ellsbury | 84 | 18 | 10 | 0.284 | 0.405 | 0.95 | CF-LF-RF |
| Jason Varitek | 65 | 6 | 6 | 0.262 | 0.308 | -0.28 | CR |
| Sean Casey | 59 | 6 | 8 | 0.346 | 0.424 | 0.07 | 1B-DH |
| Coco Crisp | 48 | 5 | 5 | 0.341 | 0.354 | -0.09 | CF |
| Kevin Cash | 35 | 2 | 3 | 0.323 | 0.371 | -0.31 | CR |
| Mike Lowell | 34 | 1 | 0 | 0.200 | 0.294 | -0.70 | 3B |
| Jed Lowrie | 30 | 4 | 5 | 0.346 | 0.367 | 0.23 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Brandon Moss | 8 | 1 | 2 | 0.250 | 0.250 | 0.13 | LF-RF |
| Alex Cora | 5 | 0 | 0 | 1.000 | 1.000 | -0.12 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 31.7 | 5.40 | 6 | 0 | X | -0.86 |
| Tim Wakefield | 31.0 | 4.06 | 5 | 0 | X | 0.13 |
| Daisuke Matsuzaka | 28.7 | 3.14 | 5 | 0 | X | 0.74 |
| Clay Buchholz | 20.7 | 4.79 | 4 | 0 | X | -0.27 |
| Josh Beckett | 19.3 | 5.12 | 3 | 0 | X | -0.40 |
| David Aardsma | 13.7 | 3.29 | 0 | 12 | X | 0.30 |
| Jonathan Papelbon | 11.0 | 2.45 | 0 | 10 | X | 0.46 |
| Manny Delcarmen | 10.7 | 5.06 | 0 | 12 | X | -0.20 |
| Julian Tavarez | 10.3 | 5.23 | 0 | 7 | X | -0.24 |
| Javier Lopez | 10.0 | 4.50 | 0 | 13 | X | -0.06 |
| Hideki Okajima | 9.3 | 0.96 | 0 | 10 | X | 0.71 |
| Mike Timlin | 6.0 | 13.50 | 0 | 9 | X | -1.30 |
| Justin Masterson | 6.0 | 1.50 | 1 | 0 | X | 0.38 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Craig Hansen | 1.7 | 5.40 | 0 | 1 | X | -0.05 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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