| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 110 | 14 | 13 | 0.347 | 0.391 | 0.19 | 2B |
| David Ortiz | 105 | 16 | 20 | 0.189 | 0.305 | 1.26 | DH |
| Kevin Youkilis | 99 | 16 | 14 | 0.345 | 0.424 | 0.77 | 1B-3B |
| Manny Ramirez | 97 | 17 | 20 | 0.356 | 0.423 | 1.55 | LF |
| Julio Lugo | 86 | 7 | 5 | 0.321 | 0.349 | -0.81 | SS |
| J.D. Drew | 80 | 16 | 13 | 0.284 | 0.388 | 1.12 | RF |
| Jacoby Ellsbury | 78 | 18 | 9 | 0.290 | 0.423 | 0.96 | CF-LF-RF |
| Jason Varitek | 64 | 6 | 6 | 0.262 | 0.297 | -0.28 | CR |
| Sean Casey | 58 | 5 | 8 | 0.346 | 0.414 | -0.03 | 1B-DH |
| Coco Crisp | 48 | 5 | 5 | 0.341 | 0.354 | -0.10 | CF |
| Mike Lowell | 34 | 1 | 0 | 0.200 | 0.294 | -0.71 | 3B |
| Kevin Cash | 31 | 2 | 2 | 0.250 | 0.323 | -0.33 | CR |
| Jed Lowrie | 26 | 4 | 5 | 0.348 | 0.346 | 0.32 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Brandon Moss | 8 | 1 | 2 | 0.250 | 0.250 | 0.12 | LF-RF |
| Alex Cora | 5 | 0 | 0 | 1.000 | 1.000 | -0.12 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 31.7 | 5.40 | 6 | 0 | X | -0.83 |
| Daisuke Matsuzaka | 28.7 | 3.14 | 5 | 0 | X | 0.76 |
| Tim Wakefield | 25.0 | 3.96 | 4 | 0 | X | 0.18 |
| Clay Buchholz | 20.7 | 4.79 | 4 | 0 | X | -0.25 |
| Josh Beckett | 19.3 | 5.12 | 3 | 0 | X | -0.38 |
| David Aardsma | 12.7 | 3.55 | 0 | 11 | X | 0.21 |
| Jonathan Papelbon | 11.0 | 2.45 | 0 | 10 | X | 0.47 |
| Manny Delcarmen | 10.7 | 5.06 | 0 | 12 | X | -0.20 |
| Julian Tavarez | 10.3 | 5.23 | 0 | 7 | X | -0.23 |
| Javier Lopez | 9.3 | 4.82 | 0 | 12 | X | -0.12 |
| Hideki Okajima | 9.3 | 0.96 | 0 | 10 | X | 0.72 |
| Justin Masterson | 6.0 | 1.50 | 1 | 0 | X | 0.39 |
| Mike Timlin | 5.3 | 13.50 | 0 | 8 | X | -1.15 |
| Bryan Corey | 4.3 | 14.54 | 0 | 6 | X | -1.04 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
| Craig Hansen | 1.7 | 5.40 | 0 | 1 | X | -0.04 |
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