| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 748 | 118 | 78 | 0.277 | 0.390 | 1.83 | CF |
| Casey Blake | 662 | 81 | 79 | 0.270 | 0.337 | 0.21 | 3B-1B |
| Travis Hafner | 661 | 82 | 101 | 0.265 | 0.384 | 2.65 | DH-1B |
| Jhonny Peralta | 647 | 87 | 72 | 0.270 | 0.340 | 0.48 | SS |
| Victor Martinez | 645 | 82 | 113 | 0.301 | 0.374 | 4.31 | CR-1B |
| Ryan Garko | 541 | 65 | 60 | 0.289 | 0.359 | -0.43 | 1B |
| Josh Barfield | 444 | 49 | 50 | 0.243 | 0.268 | -0.73 | 2B |
| Trot Nixon | 354 | 34 | 30 | 0.250 | 0.342 | -2.15 | RF |
| Franklin Gutierrez | 301 | 39 | 36 | 0.265 | 0.312 | 0.33 | RF |
| Jason Michaels | 295 | 42 | 39 | 0.270 | 0.322 | 1.11 | LF-RF |
| David Dellucci | 199 | 25 | 20 | 0.229 | 0.296 | -0.26 | LF |
| Kenny Lofton | 196 | 24 | 15 | 0.283 | 0.337 | -0.82 | CF |
| Asdrubal Cabrera | 186 | 30 | 22 | 0.283 | 0.344 | 0.80 | 2B |
| Kelly Shoppach | 177 | 26 | 30 | 0.261 | 0.305 | 1.44 | CR |
| Mike Rouse | 76 | 4 | 4 | 0.118 | 0.197 | -1.06 | 2B-3B-SS |
| Ben Francisco | 66 | 9 | 12 | 0.274 | 0.303 | 0.55 | LF |
| Andy Marte | 60 | 3 | 8 | 0.193 | 0.233 | -0.35 | 3B |
| Chris Gomez | 55 | 3 | 5 | 0.283 | 0.273 | -0.54 | X |
| Shin-Soo Choo | 20 | 4 | 5 | 0.294 | 0.350 | 0.44 | X |
| Luis Rivas | 11 | 2 | 4 | 0.273 | 0.273 | 0.35 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| C.C. Sabathia | 241.0 | 3.21 | 34 | 0 | X | 6.75 |
| Fausto Carmona | 215.0 | 3.06 | 32 | 0 | X | 6.80 |
| Paul Byrd | 192.3 | 4.59 | 31 | 0 | X | -0.78 |
| Jake Westbrook | 152.0 | 4.32 | 25 | 0 | X | 0.32 |
| Cliff Lee | 97.3 | 6.29 | 16 | 4 | X | -4.26 |
| Rafael Betancourt | 79.3 | 1.47 | 0 | 68 | X | 5.44 |
| Jeremy Sowers | 67.3 | 6.42 | 13 | 0 | X | -3.15 |
| Joe Borowski | 65.7 | 5.07 | 0 | 69 | X | -1.01 |
| Rafael Perez | 60.7 | 1.78 | 0 | 44 | X | 3.72 |
| Tom Mastny | 57.7 | 4.68 | 0 | 51 | X | -0.36 |
| Aaron Laffey | 49.3 | 4.56 | 9 | 0 | X | -0.17 |
| Aaron Fultz | 37.0 | 2.92 | 0 | 49 | X | 1.29 |
| Fernando Cabrera | 33.7 | 5.61 | 0 | 24 | X | -0.94 |
| Jensen Lewis | 29.3 | 2.15 | 0 | 26 | X | 1.55 |
| Jason Stanford | 26.3 | 4.44 | 2 | 6 | X | -0.02 |
| Roberto Hernandez | 26.0 | 6.23 | 0 | 28 | X | -1.10 |
| Edward Mujica | 13.0 | 8.31 | 0 | 10 | X | -1.18 |
| Jason Davis | 11.3 | 4.76 | 0 | 8 | X | -0.09 |
| Mike Koplove | 6.0 | 6.00 | 0 | 5 | X | -0.22 |
| Juan Lara | 1.3 | 13.50 | 0 | 1 | X | -0.28 |
| Matt Miller | 1.0 | 0.00 | 0 | 2 | X | 0.10 |
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