| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 657 | 104 | 71 | 0.272 | 0.382 | 2.00 | CF |
| Casey Blake | 593 | 69 | 66 | 0.268 | 0.337 | -0.61 | 3B-1B |
| Travis Hafner | 578 | 77 | 86 | 0.256 | 0.379 | 2.71 | DH-1B |
| Jhonny Peralta | 577 | 77 | 66 | 0.270 | 0.334 | 0.63 | SS |
| Victor Martinez | 573 | 72 | 100 | 0.305 | 0.373 | 3.78 | CR-1B |
| Ryan Garko | 465 | 56 | 51 | 0.295 | 0.363 | -0.36 | 1B |
| Josh Barfield | 432 | 49 | 49 | 0.245 | 0.271 | -0.48 | 2B |
| Trot Nixon | 341 | 34 | 30 | 0.256 | 0.346 | -1.78 | RF |
| Jason Michaels | 261 | 34 | 36 | 0.268 | 0.314 | 0.84 | LF-RF |
| Franklin Gutierrez | 230 | 31 | 28 | 0.266 | 0.317 | 0.46 | RF |
| David Dellucci | 196 | 25 | 20 | 0.233 | 0.301 | -0.16 | LF |
| Kelly Shoppach | 151 | 23 | 27 | 0.275 | 0.325 | 1.49 | CR |
| Kenny Lofton | 137 | 18 | 11 | 0.303 | 0.365 | -0.37 | CF |
| Asdrubal Cabrera | 98 | 15 | 10 | 0.310 | 0.347 | 0.18 | 2B |
| Mike Rouse | 76 | 4 | 4 | 0.118 | 0.197 | -1.05 | 2B-3B-SS |
| Andy Marte | 53 | 3 | 8 | 0.176 | 0.208 | -0.17 | 3B |
| Ben Francisco | 52 | 7 | 8 | 0.271 | 0.308 | 0.28 | LF |
| Chris Gomez | 32 | 1 | 3 | 0.375 | 0.375 | -0.38 | X |
| Shin-Soo Choo | 20 | 4 | 5 | 0.294 | 0.350 | 0.45 | X |
| Luis Rivas | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| C.C. Sabathia | 211.0 | 3.24 | 30 | 0 | X | 5.71 |
| Fausto Carmona | 187.0 | 3.27 | 28 | 0 | X | 4.92 |
| Paul Byrd | 168.0 | 4.34 | 27 | 0 | X | 0.24 |
| Jake Westbrook | 127.7 | 4.30 | 21 | 0 | X | 0.30 |
| Cliff Lee | 92.7 | 6.41 | 16 | 1 | X | -4.34 |
| Rafael Betancourt | 68.0 | 1.59 | 0 | 58 | X | 4.46 |
| Jeremy Sowers | 62.3 | 6.93 | 12 | 0 | X | -3.68 |
| Joe Borowski | 55.7 | 5.50 | 0 | 59 | X | -1.42 |
| Rafael Perez | 52.7 | 1.54 | 0 | 37 | X | 3.52 |
| Tom Mastny | 50.3 | 4.47 | 0 | 45 | X | -0.08 |
| Fernando Cabrera | 33.7 | 5.61 | 0 | 24 | X | -0.95 |
| Aaron Fultz | 31.0 | 3.19 | 0 | 41 | X | 0.87 |
| Aaron Laffey | 27.3 | 5.93 | 5 | 0 | X | -0.97 |
| Jason Stanford | 26.3 | 4.44 | 2 | 6 | X | -0.03 |
| Roberto Hernandez | 26.0 | 6.23 | 0 | 28 | X | -1.11 |
| Jensen Lewis | 19.7 | 3.20 | 0 | 18 | X | 0.55 |
| Edward Mujica | 13.0 | 8.31 | 0 | 10 | X | -1.19 |
| Jason Davis | 11.3 | 4.76 | 0 | 8 | X | -0.10 |
| Mike Koplove | 5.0 | 7.20 | 0 | 4 | X | -0.33 |
| Juan Lara | 1.3 | 13.50 | 0 | 1 | X | -0.28 |
| Matt Miller | 1.0 | 0.00 | 0 | 2 | X | 0.10 |
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