| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 617 | 99 | 70 | 0.279 | 0.386 | 2.40 | CF |
| Casey Blake | 563 | 67 | 61 | 0.263 | 0.336 | -0.56 | 3B-1B |
| Jhonny Peralta | 541 | 73 | 65 | 0.274 | 0.338 | 1.03 | SS |
| Travis Hafner | 536 | 70 | 78 | 0.253 | 0.377 | 2.21 | DH-1B |
| Victor Martinez | 536 | 69 | 92 | 0.303 | 0.373 | 3.57 | CR-1B |
| Ryan Garko | 428 | 52 | 47 | 0.302 | 0.369 | -0.25 | 1B |
| Josh Barfield | 427 | 49 | 49 | 0.243 | 0.269 | -0.33 | 2B |
| Trot Nixon | 337 | 34 | 30 | 0.255 | 0.344 | -1.66 | RF |
| Jason Michaels | 251 | 33 | 34 | 0.262 | 0.311 | 0.79 | LF-RF |
| David Dellucci | 196 | 25 | 20 | 0.233 | 0.301 | -0.15 | LF |
| Franklin Gutierrez | 195 | 27 | 24 | 0.270 | 0.313 | 0.51 | RF |
| Kelly Shoppach | 144 | 21 | 24 | 0.267 | 0.319 | 1.14 | CR |
| Kenny Lofton | 107 | 12 | 6 | 0.287 | 0.336 | -0.77 | CF |
| Mike Rouse | 76 | 4 | 4 | 0.118 | 0.197 | -1.05 | 2B-3B-SS |
| Asdrubal Cabrera | 62 | 10 | 10 | 0.316 | 0.323 | 0.56 | 2B |
| Andy Marte | 52 | 3 | 8 | 0.180 | 0.212 | -0.14 | 3B |
| Ben Francisco | 48 | 7 | 7 | 0.273 | 0.312 | 0.28 | LF |
| Chris Gomez | 21 | 0 | 2 | 0.381 | 0.381 | -0.31 | X |
| Shin-Soo Choo | 20 | 4 | 5 | 0.294 | 0.350 | 0.45 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| C.C. Sabathia | 203.0 | 3.37 | 29 | 0 | X | 4.80 |
| Fausto Carmona | 173.7 | 3.16 | 26 | 0 | X | 4.95 |
| Paul Byrd | 154.3 | 4.43 | 25 | 0 | X | -0.18 |
| Jake Westbrook | 115.0 | 4.38 | 19 | 0 | X | 0.00 |
| Cliff Lee | 91.7 | 6.38 | 16 | 0 | X | -4.28 |
| Rafael Betancourt | 64.0 | 1.55 | 0 | 55 | X | 4.23 |
| Jeremy Sowers | 62.3 | 6.93 | 12 | 0 | X | -3.71 |
| Joe Borowski | 53.7 | 5.53 | 0 | 57 | X | -1.44 |
| Rafael Perez | 47.7 | 1.70 | 0 | 33 | X | 2.98 |
| Tom Mastny | 47.0 | 4.60 | 0 | 43 | X | -0.23 |
| Fernando Cabrera | 33.7 | 5.61 | 0 | 24 | X | -0.97 |
| Aaron Fultz | 28.0 | 2.89 | 0 | 39 | X | 0.97 |
| Jason Stanford | 26.3 | 4.44 | 2 | 6 | X | -0.04 |
| Roberto Hernandez | 26.0 | 6.23 | 0 | 28 | X | -1.12 |
| Aaron Laffey | 17.0 | 4.76 | 3 | 0 | X | -0.15 |
| Jensen Lewis | 16.3 | 3.31 | 0 | 16 | X | 0.41 |
| Edward Mujica | 12.7 | 8.53 | 0 | 9 | X | -1.22 |
| Jason Davis | 11.3 | 4.76 | 0 | 8 | X | -0.10 |
| Mike Koplove | 4.0 | 4.50 | 0 | 3 | X | -0.01 |
| Matt Miller | 1.0 | 0.00 | 0 | 2 | X | 0.10 |
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