| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Manny Ramirez | 377 | 49 | 51 | 0.288 | 0.385 | 1.30 | LF-DH |
| David Ortiz | 376 | 59 | 57 | 0.323 | 0.439 | 3.01 | DH |
| Kevin Youkilis | 360 | 51 | 46 | 0.320 | 0.414 | 1.40 | 1B-3B |
| Julio Lugo | 355 | 37 | 39 | 0.209 | 0.273 | -0.68 | SS |
| Mike Lowell | 352 | 40 | 66 | 0.301 | 0.349 | 2.54 | 3B |
| Coco Crisp | 337 | 45 | 29 | 0.268 | 0.320 | -0.45 | CF |
| J.D. Drew | 311 | 51 | 34 | 0.260 | 0.370 | 1.34 | RF |
| Dustin Pedroia | 294 | 39 | 26 | 0.309 | 0.388 | -0.35 | 2B |
| Jason Varitek | 291 | 34 | 38 | 0.278 | 0.364 | 0.46 | CR |
| Alex Cora | 146 | 16 | 15 | 0.279 | 0.315 | -0.31 | 2B-SS |
| Wily Mo Pena | 134 | 13 | 12 | 0.213 | 0.284 | -0.64 | LF |
| Eric Hinske | 113 | 14 | 12 | 0.196 | 0.301 | -0.03 | 1B-LF-RF |
| Doug Mirabelli | 89 | 3 | 9 | 0.185 | 0.258 | -0.91 | CR |
| Jacoby Ellsbury | 18 | 3 | 1 | 0.375 | 0.444 | -0.02 | LF-CF |
| Jeff Bailey | 9 | 1 | 1 | 0.111 | 0.111 | -0.01 | X |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 125.7 | 3.94 | 19 | 0 | X | 1.27 |
| Tim Wakefield | 112.7 | 4.47 | 18 | 0 | X | -0.27 |
| Josh Beckett | 110.0 | 3.35 | 17 | 0 | X | 2.61 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.38 |
| Julian Tavarez | 92.7 | 5.15 | 17 | 0 | X | -1.68 |
| Hideki Okajima | 45.3 | 0.79 | 0 | 41 | X | 3.78 |
| Jonathan Papelbon | 33.7 | 1.87 | 0 | 33 | X | 1.96 |
| Kyle Snyder | 33.7 | 3.21 | 0 | 29 | X | 0.91 |
| Joel Pineiro | 31.0 | 4.94 | 0 | 28 | X | -0.41 |
| Mike Timlin | 28.0 | 3.86 | 0 | 24 | X | 0.34 |
| Javier Lopez | 24.3 | 2.96 | 0 | 35 | X | 0.80 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.64 |
| Kason Gabbard | 20.3 | 4.87 | 4 | 0 | X | -0.24 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Manny Delcarmen | 13.7 | 1.32 | 0 | 12 | X | 0.97 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
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