| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Manny Ramirez | 373 | 49 | 51 | 0.286 | 0.383 | 1.40 | LF-DH |
| David Ortiz | 372 | 59 | 56 | 0.320 | 0.438 | 3.00 | DH |
| Kevin Youkilis | 356 | 51 | 46 | 0.323 | 0.416 | 1.50 | 1B-3B |
| Julio Lugo | 351 | 37 | 39 | 0.208 | 0.274 | -0.58 | SS |
| Mike Lowell | 348 | 40 | 66 | 0.302 | 0.351 | 2.64 | 3B |
| Coco Crisp | 333 | 45 | 29 | 0.265 | 0.318 | -0.35 | CF |
| J.D. Drew | 311 | 51 | 34 | 0.260 | 0.370 | 1.34 | RF |
| Dustin Pedroia | 293 | 39 | 26 | 0.310 | 0.389 | -0.32 | 2B |
| Jason Varitek | 291 | 34 | 38 | 0.278 | 0.364 | 0.46 | CR |
| Alex Cora | 143 | 15 | 15 | 0.278 | 0.315 | -0.34 | 2B-SS |
| Wily Mo Pena | 134 | 13 | 12 | 0.213 | 0.284 | -0.64 | LF |
| Eric Hinske | 109 | 14 | 12 | 0.194 | 0.303 | 0.07 | 1B-LF-RF |
| Doug Mirabelli | 85 | 3 | 9 | 0.182 | 0.259 | -0.81 | CR |
| Jacoby Ellsbury | 18 | 3 | 1 | 0.375 | 0.444 | -0.02 | LF-CF |
| Jeff Bailey | 9 | 1 | 1 | 0.111 | 0.111 | -0.01 | X |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 125.7 | 3.94 | 19 | 0 | X | 1.28 |
| Tim Wakefield | 112.7 | 4.47 | 18 | 0 | X | -0.26 |
| Josh Beckett | 102.0 | 3.44 | 16 | 0 | X | 2.22 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.39 |
| Julian Tavarez | 92.7 | 5.15 | 17 | 0 | X | -1.67 |
| Hideki Okajima | 45.3 | 0.79 | 0 | 41 | X | 3.79 |
| Kyle Snyder | 33.7 | 3.21 | 0 | 29 | X | 0.92 |
| Jonathan Papelbon | 33.7 | 1.87 | 0 | 33 | X | 1.97 |
| Joel Pineiro | 31.0 | 4.94 | 0 | 28 | X | -0.41 |
| Mike Timlin | 27.0 | 4.00 | 0 | 23 | X | 0.24 |
| Javier Lopez | 24.3 | 2.96 | 0 | 35 | X | 0.80 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.64 |
| Kason Gabbard | 20.3 | 4.87 | 4 | 0 | X | -0.23 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Manny Delcarmen | 13.7 | 1.32 | 0 | 12 | X | 0.97 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
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