| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Manny Ramirez | 358 | 46 | 44 | 0.284 | 0.385 | 0.73 | LF-DH |
| David Ortiz | 357 | 55 | 52 | 0.314 | 0.434 | 2.54 | DH |
| Kevin Youkilis | 344 | 50 | 44 | 0.328 | 0.419 | 1.49 | 1B-3B |
| Julio Lugo | 339 | 35 | 39 | 0.197 | 0.265 | -0.49 | SS |
| Mike Lowell | 336 | 39 | 63 | 0.300 | 0.351 | 2.53 | 3B |
| Coco Crisp | 320 | 43 | 28 | 0.265 | 0.316 | -0.34 | CF |
| J.D. Drew | 304 | 48 | 34 | 0.258 | 0.368 | 1.21 | RF |
| Jason Varitek | 283 | 33 | 36 | 0.279 | 0.367 | 0.35 | CR |
| Dustin Pedroia | 278 | 36 | 25 | 0.318 | 0.396 | -0.37 | 2B |
| Alex Cora | 143 | 15 | 15 | 0.278 | 0.315 | -0.33 | 2B-SS |
| Wily Mo Pena | 132 | 13 | 12 | 0.208 | 0.280 | -0.59 | LF |
| Eric Hinske | 104 | 13 | 11 | 0.193 | 0.308 | -0.01 | 1B-LF-RF |
| Doug Mirabelli | 81 | 3 | 9 | 0.189 | 0.259 | -0.71 | CR |
| Jacoby Ellsbury | 18 | 3 | 1 | 0.375 | 0.444 | -0.02 | LF-CF |
| Jeff Bailey | 9 | 1 | 1 | 0.111 | 0.111 | -0.01 | X |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 119.7 | 3.84 | 18 | 0 | X | 1.49 |
| Tim Wakefield | 106.7 | 4.39 | 17 | 0 | X | -0.04 |
| Josh Beckett | 102.0 | 3.44 | 16 | 0 | X | 2.21 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.38 |
| Julian Tavarez | 88.7 | 4.97 | 16 | 0 | X | -1.25 |
| Hideki Okajima | 43.3 | 0.83 | 0 | 39 | X | 3.58 |
| Jonathan Papelbon | 32.7 | 1.93 | 0 | 32 | X | 1.86 |
| Kyle Snyder | 32.0 | 2.81 | 0 | 28 | X | 1.16 |
| Joel Pineiro | 30.3 | 5.04 | 0 | 27 | X | -0.48 |
| Mike Timlin | 24.7 | 4.38 | 0 | 22 | X | 0.00 |
| Javier Lopez | 24.0 | 3.00 | 0 | 34 | X | 0.77 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.64 |
| Kason Gabbard | 20.3 | 4.87 | 4 | 0 | X | -0.24 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Manny Delcarmen | 10.7 | 1.69 | 0 | 10 | X | 0.67 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
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