| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Manny Ramirez | 351 | 46 | 44 | 0.289 | 0.387 | 0.85 | LF-DH |
| David Ortiz | 346 | 54 | 49 | 0.312 | 0.425 | 2.33 | DH |
| Kevin Youkilis | 343 | 50 | 44 | 0.329 | 0.420 | 1.46 | 1B-3B |
| Julio Lugo | 333 | 33 | 37 | 0.190 | 0.258 | -0.81 | SS |
| Mike Lowell | 325 | 39 | 62 | 0.307 | 0.360 | 2.64 | 3B |
| Coco Crisp | 309 | 42 | 28 | 0.266 | 0.317 | -0.22 | CF |
| J.D. Drew | 294 | 47 | 34 | 0.263 | 0.374 | 1.30 | RF |
| Jason Varitek | 272 | 33 | 36 | 0.274 | 0.364 | 0.58 | CR |
| Dustin Pedroia | 269 | 35 | 25 | 0.316 | 0.394 | -0.29 | 2B |
| Alex Cora | 138 | 15 | 15 | 0.281 | 0.319 | -0.23 | 2B-SS |
| Wily Mo Pena | 128 | 13 | 12 | 0.216 | 0.289 | -0.51 | LF |
| Eric Hinske | 100 | 13 | 11 | 0.202 | 0.320 | 0.07 | 1B-LF-RF |
| Doug Mirabelli | 81 | 3 | 9 | 0.189 | 0.259 | -0.73 | CR |
| Jacoby Ellsbury | 18 | 3 | 1 | 0.375 | 0.444 | -0.02 | LF-CF |
| Jeff Bailey | 4 | 0 | 0 | 0.000 | 0.000 | -0.10 | X |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 114.7 | 3.53 | 17 | 0 | X | 2.30 |
| Tim Wakefield | 106.7 | 4.39 | 17 | 0 | X | 0.01 |
| Josh Beckett | 102.0 | 3.44 | 16 | 0 | X | 2.27 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.43 |
| Julian Tavarez | 88.7 | 4.97 | 16 | 0 | X | -1.20 |
| Hideki Okajima | 41.0 | 0.88 | 0 | 38 | X | 3.36 |
| Kyle Snyder | 32.0 | 2.81 | 0 | 28 | X | 1.18 |
| Jonathan Papelbon | 32.0 | 1.69 | 0 | 31 | X | 2.02 |
| Joel Pineiro | 30.3 | 5.04 | 0 | 27 | X | -0.46 |
| Javier Lopez | 22.3 | 3.22 | 0 | 32 | X | 0.61 |
| Mike Timlin | 21.3 | 5.06 | 0 | 20 | X | -0.33 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.65 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.58 |
| Kason Gabbard | 14.0 | 5.79 | 3 | 0 | X | -0.45 |
| Manny Delcarmen | 9.3 | 1.93 | 0 | 9 | X | 0.54 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
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