| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Manny Ramirez | 347 | 46 | 44 | 0.289 | 0.389 | 0.98 | LF-DH |
| David Ortiz | 346 | 54 | 49 | 0.312 | 0.425 | 2.37 | DH |
| Kevin Youkilis | 343 | 50 | 44 | 0.329 | 0.420 | 1.50 | 1B-3B |
| Julio Lugo | 329 | 32 | 37 | 0.192 | 0.258 | -0.78 | SS |
| Mike Lowell | 321 | 39 | 62 | 0.307 | 0.358 | 2.77 | 3B |
| Coco Crisp | 305 | 42 | 27 | 0.265 | 0.315 | -0.20 | CF |
| J.D. Drew | 291 | 47 | 34 | 0.265 | 0.375 | 1.41 | RF |
| Jason Varitek | 269 | 33 | 36 | 0.277 | 0.368 | 0.68 | CR |
| Dustin Pedroia | 265 | 35 | 25 | 0.322 | 0.400 | -0.17 | 2B |
| Alex Cora | 138 | 15 | 15 | 0.281 | 0.319 | -0.22 | 2B-SS |
| Wily Mo Pena | 124 | 13 | 12 | 0.212 | 0.282 | -0.40 | LF |
| Eric Hinske | 99 | 13 | 11 | 0.205 | 0.323 | 0.10 | 1B-LF-RF |
| Doug Mirabelli | 80 | 2 | 8 | 0.178 | 0.250 | -0.90 | CR |
| Jacoby Ellsbury | 18 | 3 | 1 | 0.375 | 0.444 | -0.02 | LF-CF |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 114.7 | 3.53 | 17 | 0 | X | 2.24 |
| Tim Wakefield | 106.7 | 4.39 | 17 | 0 | X | -0.04 |
| Josh Beckett | 102.0 | 3.44 | 16 | 0 | X | 2.21 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.38 |
| Julian Tavarez | 84.0 | 4.39 | 15 | 0 | X | -0.05 |
| Hideki Okajima | 41.0 | 0.88 | 0 | 38 | X | 3.34 |
| Jonathan Papelbon | 32.0 | 1.69 | 0 | 31 | X | 2.00 |
| Kyle Snyder | 31.0 | 2.61 | 0 | 27 | X | 1.27 |
| Joel Pineiro | 30.3 | 5.04 | 0 | 27 | X | -0.48 |
| Mike Timlin | 21.3 | 5.06 | 0 | 20 | X | -0.34 |
| Javier Lopez | 21.0 | 3.43 | 0 | 31 | X | 0.46 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.64 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Kason Gabbard | 14.0 | 5.79 | 3 | 0 | X | -0.46 |
| Manny Delcarmen | 8.3 | 2.16 | 0 | 8 | X | 0.43 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
_