| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 310 | 45 | 36 | 0.331 | 0.413 | 0.90 | 1B-3B |
| Manny Ramirez | 303 | 40 | 41 | 0.304 | 0.403 | 1.07 | LF-DH |
| Julio Lugo | 299 | 31 | 33 | 0.198 | 0.258 | -0.62 | SS |
| David Ortiz | 291 | 47 | 46 | 0.326 | 0.443 | 2.62 | DH |
| Mike Lowell | 272 | 33 | 50 | 0.299 | 0.357 | 2.04 | 3B |
| Coco Crisp | 268 | 35 | 21 | 0.258 | 0.306 | -0.70 | CF |
| J.D. Drew | 246 | 41 | 31 | 0.243 | 0.346 | 1.52 | RF |
| Jason Varitek | 230 | 29 | 32 | 0.268 | 0.361 | 0.76 | CR |
| Dustin Pedroia | 216 | 31 | 23 | 0.323 | 0.394 | 0.37 | 2B |
| Alex Cora | 110 | 10 | 14 | 0.278 | 0.309 | -0.18 | 2B-SS |
| Wily Mo Pena | 110 | 13 | 11 | 0.222 | 0.300 | -0.18 | LF |
| Eric Hinske | 76 | 11 | 7 | 0.185 | 0.289 | 0.03 | 1B-LF-RF |
| Doug Mirabelli | 67 | 2 | 5 | 0.194 | 0.254 | -0.91 | CR |
| David Murphy | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 98.7 | 4.01 | 15 | 0 | X | 0.81 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.36 |
| Tim Wakefield | 88.3 | 4.18 | 14 | 0 | X | 0.38 |
| Josh Beckett | 83.0 | 3.14 | 13 | 0 | X | 2.36 |
| Julian Tavarez | 74.0 | 4.50 | 13 | 0 | X | -0.24 |
| Hideki Okajima | 36.7 | 0.98 | 0 | 33 | X | 2.89 |
| Joel Pineiro | 30.0 | 4.80 | 0 | 26 | X | -0.31 |
| Jonathan Papelbon | 26.3 | 1.71 | 0 | 26 | X | 1.63 |
| Kyle Snyder | 24.3 | 2.96 | 0 | 22 | X | 0.80 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.63 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Javier Lopez | 16.3 | 2.76 | 0 | 25 | X | 0.61 |
| Mike Timlin | 14.0 | 5.79 | 0 | 14 | X | -0.46 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.09 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
| Manny Delcarmen | 3.3 | 0.00 | 0 | 4 | X | 0.34 |
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