| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 306 | 45 | 35 | 0.332 | 0.415 | 0.91 | 1B-3B |
| Manny Ramirez | 299 | 39 | 41 | 0.300 | 0.401 | 1.08 | LF-DH |
| Julio Lugo | 295 | 31 | 33 | 0.201 | 0.261 | -0.50 | SS |
| David Ortiz | 287 | 47 | 46 | 0.332 | 0.449 | 2.74 | DH |
| Mike Lowell | 272 | 33 | 50 | 0.299 | 0.357 | 2.05 | 3B |
| Coco Crisp | 264 | 35 | 21 | 0.250 | 0.299 | -0.59 | CF |
| J.D. Drew | 246 | 41 | 31 | 0.243 | 0.346 | 1.54 | RF |
| Jason Varitek | 226 | 29 | 31 | 0.265 | 0.354 | 0.77 | CR |
| Dustin Pedroia | 212 | 30 | 23 | 0.323 | 0.396 | 0.37 | 2B |
| Alex Cora | 110 | 10 | 14 | 0.278 | 0.309 | -0.17 | 2B-SS |
| Wily Mo Pena | 107 | 13 | 11 | 0.229 | 0.308 | -0.10 | LF |
| Eric Hinske | 75 | 11 | 7 | 0.188 | 0.293 | 0.05 | 1B-LF-RF |
| Doug Mirabelli | 67 | 2 | 5 | 0.194 | 0.254 | -0.91 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.37 |
| Daisuke Matsuzaka | 92.7 | 4.18 | 14 | 0 | X | 0.41 |
| Tim Wakefield | 88.3 | 4.18 | 14 | 0 | X | 0.38 |
| Josh Beckett | 83.0 | 3.14 | 13 | 0 | X | 2.36 |
| Julian Tavarez | 74.0 | 4.50 | 13 | 0 | X | -0.23 |
| Hideki Okajima | 35.7 | 1.01 | 0 | 32 | X | 2.79 |
| Joel Pineiro | 30.0 | 4.80 | 0 | 26 | X | -0.31 |
| Jonathan Papelbon | 25.3 | 1.78 | 0 | 25 | X | 1.53 |
| Kyle Snyder | 24.3 | 2.96 | 0 | 22 | X | 0.80 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.63 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Javier Lopez | 16.0 | 2.81 | 0 | 24 | X | 0.58 |
| Mike Timlin | 14.0 | 5.79 | 0 | 14 | X | -0.46 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.09 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
| Manny Delcarmen | 2.7 | 0.00 | 0 | 3 | X | 0.27 |
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