| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 301 | 45 | 35 | 0.333 | 0.415 | 1.02 | 1B-3B |
| Manny Ramirez | 294 | 37 | 39 | 0.293 | 0.395 | 0.77 | LF-DH |
| Julio Lugo | 290 | 31 | 33 | 0.205 | 0.266 | -0.39 | SS |
| David Ortiz | 283 | 46 | 44 | 0.332 | 0.449 | 2.51 | DH |
| Mike Lowell | 272 | 33 | 50 | 0.299 | 0.357 | 2.05 | 3B |
| Coco Crisp | 259 | 34 | 18 | 0.247 | 0.297 | -0.89 | CF |
| J.D. Drew | 244 | 39 | 30 | 0.236 | 0.340 | 1.26 | RF |
| Jason Varitek | 221 | 28 | 31 | 0.266 | 0.353 | 0.78 | CR |
| Dustin Pedroia | 207 | 28 | 22 | 0.320 | 0.396 | 0.17 | 2B |
| Alex Cora | 109 | 10 | 14 | 0.281 | 0.312 | -0.15 | 2B-SS |
| Wily Mo Pena | 103 | 12 | 11 | 0.217 | 0.301 | -0.11 | LF |
| Eric Hinske | 74 | 10 | 5 | 0.175 | 0.284 | -0.24 | 1B-LF-RF |
| Doug Mirabelli | 66 | 2 | 5 | 0.197 | 0.258 | -0.88 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.35 |
| Daisuke Matsuzaka | 92.7 | 4.18 | 14 | 0 | X | 0.40 |
| Tim Wakefield | 88.3 | 4.18 | 14 | 0 | X | 0.37 |
| Josh Beckett | 83.0 | 3.14 | 13 | 0 | X | 2.35 |
| Julian Tavarez | 67.0 | 4.97 | 12 | 0 | X | -0.96 |
| Hideki Okajima | 35.7 | 1.01 | 0 | 32 | X | 2.79 |
| Joel Pineiro | 29.0 | 4.97 | 0 | 25 | X | -0.41 |
| Jonathan Papelbon | 25.3 | 1.78 | 0 | 25 | X | 1.53 |
| Kyle Snyder | 24.3 | 2.96 | 0 | 22 | X | 0.79 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.63 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.56 |
| Javier Lopez | 16.0 | 2.81 | 0 | 24 | X | 0.58 |
| Mike Timlin | 13.0 | 6.23 | 0 | 13 | X | -0.57 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.09 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 2.7 | 0.00 | 0 | 3 | X | 0.27 |
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