| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 297 | 45 | 35 | 0.331 | 0.414 | 1.14 | 1B-3B |
| Manny Ramirez | 290 | 37 | 39 | 0.294 | 0.397 | 0.89 | LF-DH |
| Julio Lugo | 290 | 31 | 33 | 0.205 | 0.266 | -0.37 | SS |
| David Ortiz | 279 | 45 | 43 | 0.332 | 0.448 | 2.42 | DH |
| Mike Lowell | 272 | 33 | 50 | 0.299 | 0.357 | 2.07 | 3B |
| Coco Crisp | 255 | 34 | 18 | 0.247 | 0.298 | -0.77 | CF |
| J.D. Drew | 239 | 39 | 30 | 0.241 | 0.347 | 1.40 | RF |
| Jason Varitek | 217 | 27 | 31 | 0.259 | 0.346 | 0.78 | CR |
| Dustin Pedroia | 203 | 28 | 21 | 0.322 | 0.399 | 0.18 | 2B |
| Alex Cora | 105 | 9 | 13 | 0.277 | 0.305 | -0.26 | 2B-SS |
| Wily Mo Pena | 102 | 12 | 11 | 0.220 | 0.304 | -0.08 | LF |
| Eric Hinske | 74 | 10 | 5 | 0.175 | 0.284 | -0.23 | 1B-LF-RF |
| Doug Mirabelli | 66 | 2 | 5 | 0.197 | 0.258 | -0.88 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.33 |
| Daisuke Matsuzaka | 92.7 | 4.18 | 14 | 0 | X | 0.37 |
| Tim Wakefield | 88.3 | 4.18 | 14 | 0 | X | 0.36 |
| Josh Beckett | 77.0 | 3.39 | 12 | 0 | X | 1.72 |
| Julian Tavarez | 67.0 | 4.97 | 12 | 0 | X | -0.97 |
| Hideki Okajima | 34.7 | 1.04 | 0 | 31 | X | 2.68 |
| Joel Pineiro | 29.0 | 4.97 | 0 | 25 | X | -0.42 |
| Jonathan Papelbon | 24.3 | 1.85 | 0 | 24 | X | 1.42 |
| Kyle Snyder | 23.3 | 3.09 | 0 | 21 | X | 0.69 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.63 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.56 |
| Javier Lopez | 16.0 | 2.81 | 0 | 24 | X | 0.57 |
| Mike Timlin | 13.0 | 6.23 | 0 | 13 | X | -0.57 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.09 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 2.7 | 0.00 | 0 | 3 | X | 0.27 |
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