| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 292 | 45 | 35 | 0.332 | 0.414 | 1.27 | 1B-3B |
| Manny Ramirez | 286 | 37 | 39 | 0.293 | 0.395 | 1.00 | LF-DH |
| Julio Lugo | 286 | 31 | 33 | 0.207 | 0.266 | -0.26 | SS |
| David Ortiz | 278 | 45 | 43 | 0.333 | 0.450 | 2.45 | DH |
| Mike Lowell | 267 | 33 | 50 | 0.305 | 0.363 | 2.20 | 3B |
| Coco Crisp | 251 | 32 | 16 | 0.233 | 0.287 | -1.09 | CF |
| J.D. Drew | 234 | 38 | 29 | 0.242 | 0.350 | 1.32 | RF |
| Jason Varitek | 213 | 27 | 31 | 0.265 | 0.352 | 0.89 | CR |
| Dustin Pedroia | 198 | 27 | 21 | 0.322 | 0.394 | 0.21 | 2B |
| Alex Cora | 105 | 9 | 13 | 0.277 | 0.305 | -0.25 | 2B-SS |
| Wily Mo Pena | 101 | 12 | 11 | 0.222 | 0.307 | -0.05 | LF |
| Eric Hinske | 73 | 10 | 5 | 0.177 | 0.288 | -0.21 | 1B-LF-RF |
| Doug Mirabelli | 65 | 2 | 5 | 0.197 | 0.246 | -0.85 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 92.7 | 4.18 | 14 | 0 | X | 0.34 |
| Curt Schilling | 90.0 | 3.80 | 14 | 0 | X | 1.12 |
| Tim Wakefield | 88.3 | 4.18 | 14 | 0 | X | 0.32 |
| Josh Beckett | 77.0 | 3.39 | 12 | 0 | X | 1.69 |
| Julian Tavarez | 67.0 | 4.97 | 12 | 0 | X | -1.00 |
| Hideki Okajima | 34.7 | 1.04 | 0 | 31 | X | 2.66 |
| Joel Pineiro | 29.0 | 4.97 | 0 | 25 | X | -0.43 |
| Jonathan Papelbon | 24.3 | 1.85 | 0 | 24 | X | 1.41 |
| Kyle Snyder | 22.7 | 3.18 | 0 | 20 | X | 0.61 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.62 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.55 |
| Javier Lopez | 15.3 | 2.93 | 0 | 23 | X | 0.50 |
| Mike Timlin | 11.7 | 5.40 | 0 | 12 | X | -0.29 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.09 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.7 | 0.00 | 0 | 2 | X | 0.17 |
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