| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 288 | 44 | 33 | 0.329 | 0.413 | 1.09 | 1B-3B |
| Manny Ramirez | 282 | 36 | 36 | 0.290 | 0.394 | 0.71 | LF-DH |
| Julio Lugo | 282 | 31 | 33 | 0.210 | 0.270 | -0.13 | SS |
| David Ortiz | 274 | 43 | 42 | 0.329 | 0.445 | 2.27 | DH |
| Mike Lowell | 263 | 32 | 49 | 0.306 | 0.365 | 2.12 | 3B |
| Coco Crisp | 250 | 32 | 16 | 0.230 | 0.284 | -1.03 | CF |
| J.D. Drew | 229 | 36 | 29 | 0.241 | 0.345 | 1.27 | RF |
| Jason Varitek | 213 | 27 | 31 | 0.265 | 0.352 | 0.92 | CR |
| Dustin Pedroia | 193 | 25 | 21 | 0.324 | 0.394 | 0.14 | 2B |
| Alex Cora | 105 | 9 | 13 | 0.277 | 0.305 | -0.24 | 2B-SS |
| Wily Mo Pena | 98 | 12 | 11 | 0.230 | 0.316 | 0.04 | LF |
| Eric Hinske | 73 | 10 | 5 | 0.177 | 0.288 | -0.20 | 1B-LF-RF |
| Doug Mirabelli | 61 | 2 | 4 | 0.190 | 0.230 | -0.85 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 92.7 | 4.18 | 14 | 0 | X | 0.29 |
| Curt Schilling | 90.0 | 3.80 | 14 | 0 | X | 1.07 |
| Tim Wakefield | 82.7 | 3.92 | 13 | 0 | X | 0.76 |
| Josh Beckett | 77.0 | 3.39 | 12 | 0 | X | 1.66 |
| Julian Tavarez | 67.0 | 4.97 | 12 | 0 | X | -1.03 |
| Hideki Okajima | 33.7 | 1.07 | 0 | 30 | X | 2.55 |
| Joel Pineiro | 27.3 | 5.27 | 0 | 24 | X | -0.61 |
| Jonathan Papelbon | 24.3 | 1.85 | 0 | 24 | X | 1.40 |
| Kyle Snyder | 22.7 | 3.18 | 0 | 20 | X | 0.60 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.61 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.54 |
| Javier Lopez | 15.3 | 2.93 | 0 | 22 | X | 0.49 |
| Mike Timlin | 11.7 | 5.40 | 0 | 12 | X | -0.30 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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