| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 275 | 44 | 33 | 0.338 | 0.422 | 1.44 | 1B-3B |
| Julio Lugo | 274 | 29 | 33 | 0.211 | 0.266 | -0.11 | SS |
| Manny Ramirez | 269 | 34 | 34 | 0.289 | 0.390 | 0.64 | LF-DH |
| David Ortiz | 265 | 43 | 42 | 0.338 | 0.449 | 2.53 | DH |
| Mike Lowell | 250 | 31 | 48 | 0.314 | 0.372 | 2.26 | 3B |
| Coco Crisp | 239 | 30 | 16 | 0.221 | 0.272 | -0.94 | CF |
| J.D. Drew | 215 | 33 | 26 | 0.236 | 0.344 | 1.00 | RF |
| Jason Varitek | 202 | 27 | 31 | 0.270 | 0.361 | 1.21 | CR |
| Dustin Pedroia | 179 | 23 | 16 | 0.314 | 0.391 | -0.23 | 2B |
| Alex Cora | 102 | 9 | 13 | 0.286 | 0.314 | -0.15 | 2B-SS |
| Wily Mo Pena | 94 | 12 | 10 | 0.238 | 0.319 | 0.04 | LF |
| Eric Hinske | 73 | 10 | 5 | 0.177 | 0.288 | -0.19 | 1B-LF-RF |
| Doug Mirabelli | 61 | 2 | 4 | 0.190 | 0.230 | -0.84 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 90.0 | 3.80 | 14 | 0 | X | 1.04 |
| Daisuke Matsuzaka | 85.7 | 4.52 | 13 | 0 | X | -0.45 |
| Tim Wakefield | 82.7 | 3.92 | 13 | 0 | X | 0.72 |
| Josh Beckett | 72.0 | 2.88 | 11 | 0 | X | 2.38 |
| Julian Tavarez | 60.0 | 5.25 | 11 | 0 | X | -1.34 |
| Hideki Okajima | 31.7 | 1.14 | 0 | 28 | X | 2.33 |
| Joel Pineiro | 26.3 | 5.47 | 0 | 23 | X | -0.72 |
| Jonathan Papelbon | 23.3 | 1.93 | 0 | 23 | X | 1.29 |
| Kyle Snyder | 20.7 | 3.48 | 0 | 19 | X | 0.39 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.60 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.53 |
| Javier Lopez | 14.3 | 3.14 | 0 | 21 | X | 0.39 |
| Mike Timlin | 10.7 | 5.06 | 0 | 11 | X | -0.19 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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