| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 271 | 43 | 33 | 0.335 | 0.421 | 1.45 | 1B-3B |
| Julio Lugo | 270 | 29 | 33 | 0.215 | 0.270 | 0.00 | SS |
| Manny Ramirez | 266 | 34 | 33 | 0.289 | 0.391 | 0.62 | LF-DH |
| David Ortiz | 261 | 43 | 42 | 0.340 | 0.452 | 2.63 | DH |
| Mike Lowell | 246 | 30 | 47 | 0.311 | 0.370 | 2.15 | 3B |
| Coco Crisp | 235 | 30 | 16 | 0.225 | 0.277 | -0.83 | CF |
| J.D. Drew | 211 | 33 | 26 | 0.240 | 0.346 | 1.11 | RF |
| Jason Varitek | 199 | 27 | 31 | 0.267 | 0.357 | 1.29 | CR |
| Dustin Pedroia | 179 | 23 | 16 | 0.314 | 0.391 | -0.22 | 2B |
| Alex Cora | 98 | 9 | 13 | 0.287 | 0.316 | -0.05 | 2B-SS |
| Wily Mo Pena | 93 | 12 | 10 | 0.241 | 0.323 | 0.07 | LF |
| Eric Hinske | 73 | 10 | 5 | 0.177 | 0.288 | -0.18 | 1B-LF-RF |
| Doug Mirabelli | 60 | 2 | 4 | 0.193 | 0.233 | -0.82 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 85.7 | 4.52 | 13 | 0 | X | -0.45 |
| Curt Schilling | 85.0 | 3.49 | 13 | 0 | X | 1.59 |
| Tim Wakefield | 82.7 | 3.92 | 13 | 0 | X | 0.72 |
| Josh Beckett | 72.0 | 2.88 | 11 | 0 | X | 2.38 |
| Julian Tavarez | 60.0 | 5.25 | 11 | 0 | X | -1.34 |
| Hideki Okajima | 31.7 | 1.14 | 0 | 28 | X | 2.33 |
| Joel Pineiro | 24.3 | 4.81 | 0 | 22 | X | -0.29 |
| Jonathan Papelbon | 23.3 | 1.93 | 0 | 23 | X | 1.29 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.60 |
| Kyle Snyder | 20.0 | 2.25 | 0 | 18 | X | 0.95 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.53 |
| Javier Lopez | 14.0 | 3.21 | 0 | 20 | X | 0.35 |
| Mike Timlin | 9.7 | 5.59 | 0 | 10 | X | -0.29 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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