| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 258 | 43 | 32 | 0.339 | 0.426 | 1.65 | 1B-3B |
| Manny Ramirez | 258 | 33 | 33 | 0.293 | 0.384 | 0.71 | LF-DH |
| Julio Lugo | 257 | 28 | 33 | 0.217 | 0.276 | 0.21 | SS |
| David Ortiz | 252 | 42 | 42 | 0.337 | 0.448 | 2.74 | DH |
| Mike Lowell | 237 | 30 | 45 | 0.313 | 0.376 | 2.16 | 3B |
| Coco Crisp | 222 | 30 | 16 | 0.225 | 0.279 | -0.52 | CF |
| J.D. Drew | 201 | 31 | 25 | 0.235 | 0.348 | 1.03 | RF |
| Jason Varitek | 190 | 26 | 28 | 0.270 | 0.363 | 1.09 | CR |
| Dustin Pedroia | 170 | 22 | 16 | 0.318 | 0.394 | -0.11 | 2B |
| Alex Cora | 92 | 9 | 13 | 0.293 | 0.326 | 0.09 | 2B-SS |
| Wily Mo Pena | 89 | 12 | 10 | 0.241 | 0.326 | 0.16 | LF |
| Eric Hinske | 68 | 10 | 5 | 0.169 | 0.265 | -0.06 | 1B-LF-RF |
| Doug Mirabelli | 57 | 2 | 4 | 0.204 | 0.246 | -0.74 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 85.0 | 3.49 | 13 | 0 | X | 1.61 |
| Daisuke Matsuzaka | 79.7 | 4.63 | 12 | 0 | X | -0.61 |
| Tim Wakefield | 74.7 | 4.22 | 12 | 0 | X | 0.15 |
| Josh Beckett | 72.0 | 2.88 | 11 | 0 | X | 2.40 |
| Julian Tavarez | 54.0 | 5.33 | 10 | 0 | X | -1.30 |
| Hideki Okajima | 29.7 | 1.21 | 0 | 27 | X | 2.14 |
| Joel Pineiro | 24.3 | 4.81 | 0 | 22 | X | -0.29 |
| Jonathan Papelbon | 21.3 | 2.11 | 0 | 21 | X | 1.09 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.54 |
| Kyle Snyder | 20.0 | 2.25 | 0 | 18 | X | 0.96 |
| Brendan Donnelly | 18.7 | 3.37 | 0 | 25 | X | 0.40 |
| Javier Lopez | 14.0 | 3.21 | 0 | 19 | X | 0.36 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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