| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 249 | 42 | 31 | 0.341 | 0.426 | 1.68 | 1B-3B |
| Manny Ramirez | 246 | 30 | 32 | 0.283 | 0.374 | 0.59 | LF-DH |
| Julio Lugo | 244 | 26 | 32 | 0.225 | 0.283 | 0.22 | SS |
| David Ortiz | 240 | 40 | 41 | 0.332 | 0.442 | 2.73 | DH |
| Mike Lowell | 224 | 30 | 45 | 0.330 | 0.388 | 2.49 | 3B |
| Coco Crisp | 211 | 30 | 16 | 0.233 | 0.289 | -0.24 | CF |
| J.D. Drew | 191 | 29 | 18 | 0.224 | 0.340 | 0.34 | RF |
| Jason Varitek | 180 | 26 | 28 | 0.275 | 0.372 | 1.34 | CR |
| Dustin Pedroia | 161 | 20 | 16 | 0.329 | 0.404 | -0.09 | 2B |
| Alex Cora | 89 | 9 | 13 | 0.304 | 0.337 | 0.17 | 2B-SS |
| Wily Mo Pena | 86 | 12 | 9 | 0.237 | 0.326 | 0.14 | LF |
| Eric Hinske | 67 | 9 | 5 | 0.155 | 0.254 | -0.14 | 1B-LF-RF |
| Doug Mirabelli | 53 | 2 | 4 | 0.180 | 0.226 | -0.64 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 79.7 | 4.63 | 12 | 0 | X | -0.64 |
| Curt Schilling | 76.0 | 3.91 | 12 | 0 | X | 0.68 |
| Tim Wakefield | 68.0 | 4.24 | 11 | 0 | X | 0.08 |
| Josh Beckett | 64.0 | 2.95 | 10 | 0 | X | 1.99 |
| Julian Tavarez | 54.0 | 5.33 | 10 | 0 | X | -1.32 |
| Hideki Okajima | 28.3 | 1.27 | 0 | 26 | X | 2.00 |
| Joel Pineiro | 23.3 | 5.01 | 0 | 21 | X | -0.40 |
| Jonathan Papelbon | 21.3 | 2.11 | 0 | 21 | X | 1.08 |
| Kyle Snyder | 20.0 | 2.25 | 0 | 18 | X | 0.95 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.53 |
| Brendan Donnelly | 18.7 | 3.37 | 0 | 25 | X | 0.40 |
| Javier Lopez | 14.0 | 3.21 | 0 | 19 | X | 0.35 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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