| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 240 | 42 | 31 | 0.350 | 0.433 | 1.89 | 1B-3B |
| Julio Lugo | 238 | 26 | 32 | 0.226 | 0.286 | 0.36 | SS |
| Manny Ramirez | 237 | 30 | 32 | 0.288 | 0.376 | 0.81 | LF-DH |
| David Ortiz | 231 | 38 | 40 | 0.325 | 0.437 | 2.63 | DH |
| Mike Lowell | 219 | 30 | 45 | 0.333 | 0.393 | 2.60 | 3B |
| Coco Crisp | 207 | 30 | 16 | 0.238 | 0.295 | -0.15 | CF |
| J.D. Drew | 188 | 29 | 18 | 0.222 | 0.340 | 0.41 | RF |
| Jason Varitek | 175 | 25 | 27 | 0.275 | 0.371 | 1.25 | CR |
| Dustin Pedroia | 152 | 20 | 16 | 0.336 | 0.408 | 0.12 | 2B |
| Alex Cora | 86 | 9 | 13 | 0.316 | 0.349 | 0.24 | 2B-SS |
| Wily Mo Pena | 78 | 11 | 7 | 0.229 | 0.308 | 0.01 | LF |
| Eric Hinske | 64 | 9 | 5 | 0.164 | 0.266 | -0.07 | 1B-LF-RF |
| Doug Mirabelli | 49 | 2 | 4 | 0.196 | 0.245 | -0.55 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 76.0 | 3.91 | 12 | 0 | X | 0.70 |
| Daisuke Matsuzaka | 72.7 | 4.83 | 11 | 0 | X | -0.90 |
| Tim Wakefield | 68.0 | 4.24 | 11 | 0 | X | 0.10 |
| Josh Beckett | 64.0 | 2.95 | 10 | 0 | X | 2.01 |
| Julian Tavarez | 48.3 | 5.40 | 9 | 0 | X | -1.24 |
| Hideki Okajima | 28.3 | 1.27 | 0 | 26 | X | 2.00 |
| Joel Pineiro | 22.3 | 5.24 | 0 | 20 | X | -0.49 |
| Jonathan Papelbon | 21.3 | 2.11 | 0 | 21 | X | 1.09 |
| J.C. Romero | 18.7 | 3.37 | 0 | 22 | X | 0.40 |
| Kyle Snyder | 18.7 | 1.93 | 0 | 17 | X | 1.03 |
| Brendan Donnelly | 17.3 | 3.63 | 0 | 24 | X | 0.27 |
| Javier Lopez | 13.0 | 3.46 | 0 | 18 | X | 0.25 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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