| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 225 | 40 | 30 | 0.354 | 0.427 | 1.93 | 1B-3B |
| Julio Lugo | 223 | 26 | 29 | 0.230 | 0.287 | 0.40 | SS |
| Manny Ramirez | 222 | 28 | 31 | 0.269 | 0.356 | 0.84 | LF-DH |
| David Ortiz | 216 | 34 | 38 | 0.315 | 0.431 | 2.35 | DH |
| Mike Lowell | 207 | 28 | 41 | 0.330 | 0.386 | 2.26 | 3B |
| Coco Crisp | 195 | 27 | 15 | 0.229 | 0.287 | -0.29 | CF |
| J.D. Drew | 185 | 29 | 18 | 0.226 | 0.346 | 0.48 | RF |
| Jason Varitek | 166 | 22 | 26 | 0.277 | 0.373 | 1.04 | CR |
| Dustin Pedroia | 138 | 18 | 11 | 0.308 | 0.391 | -0.28 | 2B |
| Alex Cora | 86 | 9 | 13 | 0.316 | 0.349 | 0.24 | 2B-SS |
| Wily Mo Pena | 67 | 8 | 6 | 0.237 | 0.328 | -0.14 | LF |
| Eric Hinske | 61 | 9 | 5 | 0.173 | 0.279 | 0.00 | 1B-LF-RF |
| Doug Mirabelli | 45 | 2 | 4 | 0.190 | 0.244 | -0.45 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 72.7 | 4.83 | 11 | 0 | X | -0.92 |
| Curt Schilling | 71.0 | 3.68 | 11 | 0 | X | 1.01 |
| Tim Wakefield | 64.3 | 3.36 | 10 | 0 | X | 1.40 |
| Josh Beckett | 57.7 | 2.65 | 9 | 0 | X | 2.20 |
| Julian Tavarez | 48.3 | 5.40 | 9 | 0 | X | -1.25 |
| Hideki Okajima | 25.7 | 1.05 | 0 | 24 | X | 1.94 |
| Joel Pineiro | 21.0 | 5.14 | 0 | 18 | X | -0.42 |
| Jonathan Papelbon | 19.3 | 1.86 | 0 | 19 | X | 1.09 |
| Kyle Snyder | 17.7 | 1.53 | 0 | 16 | X | 1.14 |
| Brendan Donnelly | 17.0 | 3.71 | 0 | 23 | X | 0.23 |
| J.C. Romero | 16.3 | 3.86 | 0 | 21 | X | 0.16 |
| Javier Lopez | 10.7 | 3.38 | 0 | 15 | X | 0.23 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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