| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Julio Lugo | 219 | 25 | 29 | 0.230 | 0.288 | 0.40 | SS |
| Kevin Youkilis | 216 | 39 | 28 | 0.354 | 0.431 | 1.84 | 1B-3B |
| Manny Ramirez | 214 | 27 | 31 | 0.267 | 0.350 | 0.94 | LF-DH |
| David Ortiz | 212 | 34 | 38 | 0.316 | 0.434 | 2.46 | DH |
| Mike Lowell | 199 | 26 | 39 | 0.328 | 0.387 | 2.04 | 3B |
| Coco Crisp | 186 | 27 | 15 | 0.240 | 0.301 | -0.06 | CF |
| J.D. Drew | 177 | 27 | 17 | 0.238 | 0.362 | 0.36 | RF |
| Jason Varitek | 158 | 21 | 24 | 0.269 | 0.367 | 0.93 | CR |
| Dustin Pedroia | 131 | 18 | 10 | 0.298 | 0.382 | -0.21 | 2B |
| Alex Cora | 82 | 9 | 13 | 0.319 | 0.354 | 0.34 | 2B-SS |
| Wily Mo Pena | 63 | 8 | 6 | 0.250 | 0.333 | -0.04 | LF |
| Eric Hinske | 61 | 9 | 5 | 0.173 | 0.279 | 0.00 | 1B-LF-RF |
| Doug Mirabelli | 45 | 2 | 4 | 0.190 | 0.244 | -0.45 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 71.0 | 3.68 | 11 | 0 | X | 1.02 |
| Daisuke Matsuzaka | 67.0 | 4.43 | 10 | 0 | X | -0.22 |
| Tim Wakefield | 64.3 | 3.36 | 10 | 0 | X | 1.40 |
| Josh Beckett | 50.7 | 2.66 | 8 | 0 | X | 1.92 |
| Julian Tavarez | 48.3 | 5.40 | 9 | 0 | X | -1.25 |
| Hideki Okajima | 24.7 | 1.09 | 0 | 23 | X | 1.84 |
| Joel Pineiro | 20.0 | 5.40 | 0 | 17 | X | -0.52 |
| Jonathan Papelbon | 19.3 | 1.86 | 0 | 19 | X | 1.10 |
| Brendan Donnelly | 16.3 | 3.86 | 0 | 22 | X | 0.17 |
| Kyle Snyder | 16.3 | 1.65 | 0 | 15 | X | 1.01 |
| J.C. Romero | 15.3 | 2.93 | 0 | 20 | X | 0.49 |
| Javier Lopez | 10.3 | 3.48 | 0 | 14 | X | 0.19 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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