| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Julio Lugo | 214 | 25 | 28 | 0.225 | 0.285 | 0.42 | SS |
| David Ortiz | 212 | 34 | 38 | 0.316 | 0.434 | 2.46 | DH |
| Kevin Youkilis | 211 | 37 | 27 | 0.353 | 0.431 | 1.65 | 1B-3B |
| Manny Ramirez | 210 | 26 | 30 | 0.268 | 0.352 | 0.83 | LF-DH |
| Mike Lowell | 195 | 26 | 38 | 0.329 | 0.390 | 2.03 | 3B |
| Coco Crisp | 181 | 27 | 15 | 0.245 | 0.304 | 0.06 | CF |
| J.D. Drew | 173 | 26 | 16 | 0.234 | 0.353 | 0.25 | RF |
| Jason Varitek | 154 | 21 | 24 | 0.275 | 0.370 | 1.02 | CR |
| Dustin Pedroia | 127 | 17 | 10 | 0.279 | 0.362 | -0.22 | 2B |
| Alex Cora | 82 | 9 | 13 | 0.319 | 0.354 | 0.34 | 2B-SS |
| Eric Hinske | 61 | 9 | 5 | 0.173 | 0.279 | 0.00 | 1B-LF-RF |
| Wily Mo Pena | 59 | 8 | 6 | 0.269 | 0.356 | 0.05 | LF |
| Doug Mirabelli | 45 | 2 | 4 | 0.190 | 0.244 | -0.45 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 67.0 | 4.43 | 10 | 0 | X | -0.22 |
| Tim Wakefield | 64.3 | 3.36 | 10 | 0 | X | 1.41 |
| Curt Schilling | 64.0 | 3.94 | 10 | 0 | X | 0.53 |
| Josh Beckett | 50.7 | 2.66 | 8 | 0 | X | 1.93 |
| Julian Tavarez | 48.3 | 5.40 | 9 | 0 | X | -1.25 |
| Hideki Okajima | 24.7 | 1.09 | 0 | 23 | X | 1.84 |
| Joel Pineiro | 20.0 | 5.40 | 0 | 17 | X | -0.52 |
| Jonathan Papelbon | 18.3 | 1.47 | 0 | 18 | X | 1.21 |
| Kyle Snyder | 16.3 | 1.65 | 0 | 15 | X | 1.01 |
| Brendan Donnelly | 16.0 | 3.94 | 0 | 21 | X | 0.13 |
| J.C. Romero | 15.3 | 2.35 | 0 | 19 | X | 0.70 |
| Javier Lopez | 9.7 | 3.72 | 0 | 13 | X | 0.13 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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