| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| David Ortiz | 212 | 34 | 38 | 0.316 | 0.434 | 2.48 | DH |
| Julio Lugo | 209 | 25 | 28 | 0.231 | 0.292 | 0.56 | SS |
| Kevin Youkilis | 206 | 36 | 27 | 0.352 | 0.432 | 1.68 | 1B-3B |
| Manny Ramirez | 206 | 26 | 30 | 0.272 | 0.354 | 0.94 | LF-DH |
| Mike Lowell | 191 | 25 | 37 | 0.325 | 0.387 | 1.93 | 3B |
| Coco Crisp | 176 | 27 | 15 | 0.241 | 0.301 | 0.19 | CF |
| J.D. Drew | 169 | 24 | 15 | 0.227 | 0.349 | 0.05 | RF |
| Jason Varitek | 150 | 20 | 21 | 0.276 | 0.373 | 0.71 | CR |
| Dustin Pedroia | 123 | 16 | 9 | 0.271 | 0.358 | -0.32 | 2B |
| Alex Cora | 82 | 9 | 13 | 0.319 | 0.354 | 0.35 | 2B-SS |
| Wily Mo Pena | 59 | 8 | 6 | 0.269 | 0.356 | 0.06 | LF |
| Eric Hinske | 57 | 9 | 5 | 0.188 | 0.298 | 0.10 | 1B-LF-RF |
| Doug Mirabelli | 45 | 2 | 4 | 0.190 | 0.244 | -0.45 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 67.0 | 4.43 | 10 | 0 | X | -0.24 |
| Tim Wakefield | 64.3 | 3.36 | 10 | 0 | X | 1.38 |
| Curt Schilling | 64.0 | 3.94 | 10 | 0 | X | 0.51 |
| Josh Beckett | 50.7 | 2.66 | 8 | 0 | X | 1.91 |
| Julian Tavarez | 42.7 | 5.27 | 8 | 0 | X | -0.99 |
| Hideki Okajima | 23.7 | 0.76 | 0 | 22 | X | 1.94 |
| Joel Pineiro | 18.3 | 5.89 | 0 | 16 | X | -0.69 |
| Jonathan Papelbon | 18.3 | 1.47 | 0 | 18 | X | 1.20 |
| Kyle Snyder | 16.3 | 1.65 | 0 | 15 | X | 1.00 |
| Brendan Donnelly | 16.0 | 3.94 | 0 | 21 | X | 0.13 |
| J.C. Romero | 14.7 | 2.45 | 0 | 18 | X | 0.62 |
| Javier Lopez | 9.7 | 3.72 | 0 | 13 | X | 0.12 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.40 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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