| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| David Ortiz | 207 | 33 | 38 | 0.324 | 0.440 | 2.49 | DH |
| Julio Lugo | 204 | 25 | 28 | 0.235 | 0.289 | 0.68 | SS |
| Manny Ramirez | 201 | 25 | 29 | 0.256 | 0.338 | 0.85 | LF-DH |
| Kevin Youkilis | 201 | 34 | 26 | 0.349 | 0.428 | 1.48 | 1B-3B |
| Mike Lowell | 186 | 24 | 37 | 0.329 | 0.392 | 1.95 | 3B |
| Coco Crisp | 171 | 26 | 14 | 0.242 | 0.304 | 0.10 | CF |
| J.D. Drew | 164 | 23 | 13 | 0.230 | 0.341 | -0.15 | RF |
| Jason Varitek | 150 | 20 | 21 | 0.276 | 0.373 | 0.71 | CR |
| Dustin Pedroia | 123 | 16 | 9 | 0.271 | 0.358 | -0.32 | 2B |
| Alex Cora | 78 | 9 | 12 | 0.333 | 0.372 | 0.34 | 2B-SS |
| Wily Mo Pena | 59 | 8 | 6 | 0.269 | 0.356 | 0.06 | LF |
| Eric Hinske | 57 | 9 | 5 | 0.188 | 0.298 | 0.10 | 1B-LF-RF |
| Doug Mirabelli | 41 | 2 | 4 | 0.205 | 0.244 | -0.35 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 67.0 | 4.43 | 10 | 0 | X | -0.26 |
| Curt Schilling | 64.0 | 3.94 | 10 | 0 | X | 0.49 |
| Tim Wakefield | 57.3 | 3.14 | 9 | 0 | X | 1.51 |
| Josh Beckett | 50.7 | 2.66 | 8 | 0 | X | 1.90 |
| Julian Tavarez | 42.7 | 5.27 | 8 | 0 | X | -1.00 |
| Hideki Okajima | 23.7 | 0.76 | 0 | 22 | X | 1.94 |
| Joel Pineiro | 18.3 | 5.89 | 0 | 16 | X | -0.69 |
| Jonathan Papelbon | 17.3 | 1.56 | 0 | 17 | X | 1.10 |
| Kyle Snyder | 16.3 | 1.65 | 0 | 15 | X | 1.00 |
| Brendan Donnelly | 15.0 | 4.20 | 0 | 20 | X | 0.02 |
| J.C. Romero | 14.7 | 2.45 | 0 | 18 | X | 0.62 |
| Javier Lopez | 9.7 | 3.72 | 0 | 12 | X | 0.12 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.40 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.38 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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