| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| David Ortiz | 164 | 26 | 32 | 0.311 | 0.433 | 2.24 | DH |
| Julio Lugo | 162 | 19 | 19 | 0.259 | 0.315 | 0.19 | SS |
| Manny Ramirez | 156 | 20 | 23 | 0.250 | 0.353 | 0.85 | LF-DH |
| Kevin Youkilis | 154 | 25 | 16 | 0.326 | 0.429 | 0.69 | 1B-3B |
| Mike Lowell | 146 | 19 | 30 | 0.312 | 0.377 | 1.72 | 3B |
| J.D. Drew | 134 | 19 | 12 | 0.257 | 0.366 | 0.11 | RF |
| Coco Crisp | 124 | 18 | 9 | 0.221 | 0.274 | -0.08 | CF |
| Jason Varitek | 121 | 15 | 16 | 0.272 | 0.372 | 0.41 | CR |
| Dustin Pedroia | 93 | 12 | 7 | 0.247 | 0.344 | -0.19 | 2B |
| Alex Cora | 55 | 9 | 11 | 0.417 | 0.436 | 0.81 | 2B-SS |
| Wily Mo Pena | 46 | 7 | 5 | 0.262 | 0.326 | 0.18 | LF |
| Eric Hinske | 42 | 7 | 2 | 0.182 | 0.333 | -0.04 | 1B-LF-RF |
| Doug Mirabelli | 27 | 2 | 4 | 0.280 | 0.333 | 0.00 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 52.0 | 3.63 | 8 | 0 | X | 0.68 |
| Josh Beckett | 50.7 | 2.66 | 8 | 0 | X | 1.81 |
| Tim Wakefield | 45.3 | 1.79 | 7 | 0 | X | 2.54 |
| Daisuke Matsuzaka | 45.0 | 4.80 | 7 | 0 | X | -0.64 |
| Julian Tavarez | 30.0 | 6.60 | 6 | 0 | X | -1.69 |
| Hideki Okajima | 18.7 | 0.48 | 0 | 17 | X | 1.62 |
| Joel Pineiro | 14.3 | 4.40 | 0 | 13 | X | -0.07 |
| Jonathan Papelbon | 13.3 | 1.35 | 0 | 13 | X | 0.88 |
| J.C. Romero | 12.7 | 2.84 | 0 | 16 | X | 0.40 |
| Kyle Snyder | 12.3 | 2.19 | 0 | 11 | X | 0.58 |
| Brendan Donnelly | 9.7 | 0.93 | 0 | 14 | X | 0.74 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.41 |
| Javier Lopez | 5.7 | 0.00 | 0 | 7 | X | 0.55 |
| Devern Hansack | 0.7 | 13.50 | 0 | 1 | X | -0.14 |
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